Journal of the Chemical Society Chemical Communications · 1976 · 432 citations · 0 references
Natural SciencesChemistryOrganic ChemistryHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsReaction MechanismsReaction PathwaysRetrosynthetic AnalysisFive-membered HeterocyclesRing-closure ReactionsRing-forming Reactions
A number of polyfunctional molecules have been examined as substrates for the 5-Endo-Trigonal ring-forming reaction, and it has been found that for first-row elements this is a disfavoured process, alternative reactions of type 5-Exo-Trig generally taking precedence; one case of a 5-Endo-Trig closure for a second-row element, sulphur, has been found.