Concepedia

A Concise Synthesis of (-)-Cytoxazone and its Stereoisomers via Imino 1,2-Wittig Rearrangement

Okiko Miyata, Hiroshi Asai, Takeaki Naito

Synlett · 1999 · 37 citations · 0 references

Concepts

PharmacyChemistryMedicinal ChemistrySynthetic Medicinal ChemistryRetrosynthetic AnalysisRearrangement ReactionsRearrangement TechniquesStereoselective Synthesis

Abstract

A concise synthesis of (-)-cytoxazone (1) and its stereoisomers has been achieved via the route involving the imino 1,2-Wittig rearrangement of hydroximate.