Concepedia

Catalytic Enantioselective Synthesis of Adociacetylene B

Barry M. Trost, Andrew H. Weiss

Organic Letters · 2006 · 77 citations · 12 references

DOI

Concepts

Abstract

A catalytic enantioselective total synthesis of adociacetylene B (2) in five steps is reported. The efficiency of this synthesis was enabled by an asymmetric zinc alkynylation catalyzed by the proline-derived ligand (1).

References

12

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