Dinuclear Zn-Catalyzed Asymmetric Alkynylation of Unsaturated Aldehydes

Abstract

Our recent development of a proline-derived bimetallic catalyst has led to a number of efficient, catalytic, enantioselective transformations. Herein, we report a practical and general alkynylation of aromatic and alpha,beta-unsaturated aldehydes using our zinc catalyst system.