A Dinuclear Zn Catalyst for the Asymmetric Nitroaldol (Henry) Reaction We thank the National Science Foundation and the National Institutes of Health, General Medical Sciences, for their generous support of our programs. Mass spectra were provided by the Mass Spectrometry Facility of the University of California, San Francisco, supported by the NIH Division of Research Resources.

Abstract

A high level of enantioselectivity (78–93 % ee) and high yields (58–90 %) are obtained in the enantioselective nitroaldol reaction of nitromethane with several aldehydes when a novel dinuclear zinc catalyst is employed (see scheme). Supporting information for this article is available on the WWW under http://www.angewandte.com or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.