Concepedia

Convenient Synthesis of Branched-Chain Glycosamines by Radical Addition of Nitromethane to Glycals

Elangovan Elamparuthi, Torsten Linker

Organic Letters · 2008 · 35 citations · 17 references

DOI

Concepts

Abstract

Radical addition-reduction-acetylation is the simple three-step sequence for the synthesis of branched-chain glycosamines 3 from glycals 1 and nitromethane (2). The intermediary formed 2-C-nitromethyl-pyranosides are valuable precursors for the synthesis of C-2 branched disaccharides.

References

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