Shape-Dependent Catalysis: Insights into the Source of Catalysis for the CC-1065 and Duocarmycin DNA Alkylation Reaction

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTShape-Dependent Catalysis: Insights into the Source of Catalysis for the CC-1065 and Duocarmycin DNA Alkylation ReactionDale L. Boger and Robert M. GarbaccioView Author Information Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037 Cite this: Acc. Chem. Res. 1999, 32, 12, 1043–1052Publication Date (Web):November 18, 1999Publication History Received9 April 1999Published online18 November 1999Published inissue 1 December 1999https://pubs.acs.org/doi/10.1021/ar9800946https://doi.org/10.1021/ar9800946research-articleACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views723Altmetric-Citations134LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Alcohols,Amides,Genetics,Post-translational modification,Reactivity Get e-Alerts