Diastereoselective synthesis of (2S,3R) 2-carboxy-3-pyrrolidine acetic acid, a simple kainic acid analogue

Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea

Joseph T. Coyle, Robert Schwarcz · Nature · 1976 · 1.2K citations

Life Sciences, Neurobiology, Neuroscience +14

Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic and kainic acids

Edith G. McGeer, P. L. McGeer · Nature · 1976 · 830 citations

Life Sciences, Neurology, Neuroscience +10

Conformationally defined neurotransmitter analogs. Selective inhibition of glutamate uptake by one pyrrolidine-2,4-dicarboxylate diastereomer

Richard J. Bridges, Mark Stanley, Michael W. Anderson et al. · Journal of Medicinal Chemistry · 1991 · 303 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

Total synthesis of (-)-domoic acid. A revision of the original structure

Yasufumi Ohfune, M. Tomita · Journal of the American Chemical Society · 1982 · 190 citations

Natural Sciences, Biochemistry, Chemistry +7

Studies on the Effective Principles of <i>Digenea simplex</i> Aq. I

Shinzo Murakami, TSUNEMATSU TAKEMOTO, Zensho Shimizu · YAKUGAKU ZASSHI · 1953 · 172 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +11