Bioorganic & Medicinal Chemistry Letters · 1997 · 11 citations · 15 references
PharmacyMedicinal ChemistryPharmacologyDrug DiscoveryStructure-activity RelationshipsSynthetic Medicinal ChemistryRetinoic Acid SignalingStructure-activity Relationship AnalysisBiological Activity FeaturesRetinoic Acid MetabolismRetinoic Acid Receptor SignalingRetinoic Acid SynthesisSubstituent Effects On Biological Activity
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Identification of a receptor for the morphogen retinoic acid
Vincent Giguère, Estelita S. Ong, Prudimar Segui et al. · Nature · 1987 · 2K citations
9-cis retinoic acid is a high affinity ligand for the retinoid X receptor
Richard A. Heyman, David J. Mangelsdorf, Jacqueline A. Dyck et al. · Cell · 1992 · 1.8K citations
9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα
Arthur A. Levin, Laurie J. Sturzenbecker, Sonja Kazmer et al. · Nature · 1992 · 1.2K citations
Identification of a second human retinoic acid receptor
Nigel J. Brand, Martin Petkovich, Andrée Krust et al. · Nature · 1988 · 1K citations