Synthesis of Polyfunctionalized Quinolines via the Sequence of Propargyl–Allenyl Isomerization and Aza-electrocyclization

Abstract

Quinoline derivatives are important heterocyclic compounds because of their natural occurrence and applications in pharmaceutical fields. In this paper, a sequence of propargyl-allenyl isomerization and aza-electrocyclization for the synthesis of polyfunctionalized quinolines are described.