Optimal Therapy Scheduling Based on a Pair of Collaterally Sensitive Drugs

A general method for numerically simulating the stochastic time evolution of coupled chemical reactions

Daniel T. Gillespie · Journal of Computational Physics · 1976 · 6.3K citations

Natural Sciences, Chemistry, Physics +16

The Development of Human Benign Prostatic Hyperplasia with Age

Stephen J. Berry, Donald S. Coffey, Patrick C. Walsh et al. · The Journal of Urology · 1984 · 2.5K citations

Medicine, Endocrinology, Urology +9

A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate.

Goldie Jh, Coldman Aj · PubMed · 1980 · 1.3K citations

Medicine, Cancer Biology, Oncology +16

Combination Cancer Therapy Can Confer Benefit via Patient-to-Patient Variability without Drug Additivity or Synergy

Adam C. Palmer, Peter K. Sorger · Cell · 2017 · 666 citations · Full text

Medicine, Oncology, Pharmacology +13

Rationale for the use of alternating non-cross-resistant chemotherapy.

Goldie Jh, Coldman Aj, Gudauskas Ga · PubMed · 1982 · 550 citations

Medicine, Oncology, Pharmacology +10