Synthesis of the taxol AB-system by olefination of an A-ring C1 ketone and direct B-ring closure

Tetrapropylammonium Perruthenate, Pr₄N⁺RuO₄ ^-, TPAP: A Catalytic Oxidant for Organic Synthesis

Steven V. Ley, Joanne Norman, William P. Griffith et al. · Synthesis · 1994 · 1.2K citations

Natural Sciences, Chemistry, Catalysis +10

Total synthesis of taxol

K. C. Nicolaou, Zhen Yang, Jimei Liu et al. · Nature · 1994 · 1.1K citations

Natural Sciences, Biochemistry, Chemistry +5

Direct synthesis of Z-unsaturated esters. A useful modification of the horner-emmons olefination.

W. Clark Still, Cesare Gennari · Tetrahedron Letters · 1983 · 1K citations

Natural Sciences, Chemistry, Organic Chemistry +2

Reactions of carbonyl compounds with Grignard reagents in the presence of cerium chloride

Tsuneo Imamoto, Nobuyuki Takiyama, Kimikazu Nakamura et al. · Journal of the American Chemical Society · 1989 · 615 citations

Natural Sciences, Chemistry, Analytical Chemistry +6

The synthesis of carbocyclic eight-membered rings

Nicos A. Petasis, Michael A. Patane · Tetrahedron · 1992 · 325 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11