Concepedia

A SIMPLE AND EFFICIENT METHOD FOR THE SYNTHESIS OF NITRILE OXIDE FROM ALDOXIME USING TRICHLOROISOCYANURIC ACID

Rogério da Conceição Rodrigues, Alcino Palermo de Aguiar

Synthetic Communications · 2001 · 19 citations · 16 references

DOI

Concepts

Abstract

Treatment of the aldoxime derived from vanilin with trichloroisocyanuric acid in the presence of olefins as dipolarophiles caused the formation of nitrile oxides and subsequent 1,3-dipolar cycloaddition forming the corresponding isoxazoline derivatives in good yields.

References

16

Rapid chromatographic technique for preparative separations with moderate resolution

W. Clark Still, Michaël Kahn, Abhijit Mitra · The Journal of Organic Chemistry · 1978 · 5.8K citations

, , +8

The Reactions of Primary Nitroparaffins with Isocyanates<sup>1</sup>

Teruaki Mukaiyama, Toshio Hoshino · Journal of the American Chemical Society · 1960 · 559 citations

, , +5

Nitrile oxides. X. Improved method for the prepared of nitrile oxides from aldoximes

Christoph Grundmann, R. Richter · The Journal of Organic Chemistry · 1968 · 131 citations

, , +5

A New Method for the Generation of Nitrile Oxides and Its Application to the Synthesis of 2-Isoxazolines

K. M. Lokanatha · Synthesis · 1989 · 122 citations

, , +7

Lead tetraacetate oxidation of aldoximes

George Just, Kenneth Dahl · Tetrahedron · 1968 · 79 citations

, , +8