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An Approach to Amino Ester Subunits of Tamiflu
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2007
Year
Protein ChemistryBiosynthesisTwo-step SynthesisEngineeringBiochemistryAlkene MetathesisProtein FoldingUnsaturated AldehydesNatural SciencesNitro PhosphonateOrganic ChemistryProtein EngineeringChemistryAmino Ester SubunitsStructure-function Enzyme KineticsEnzymatic ModificationSynthetic ChemistryBiomolecular Engineering
A two-step synthesis of amino cyclohexene carboxylic acid esters has been achieved in good overall yield from nitro phosphonate and unsaturated aldehydes.