Concepedia

Design, synthesis and X-ray crystallographic studies of [7.3.1] and [8.3.1] macrocyclic FKBP-12 ligands

Robert E. Babine, Ted M. Bleckman, Ethel S. Littlefield, Hans E. Parge, Laura A. Pelletier, Cristina Lewis, J. V. FRENCH, Michael Imbacuan, Susumo Katoh, John H. Tatlock,

Bioorganic & Medicinal Chemistry Letters · 1996 · 11 citations · 15 references

DOI

Concepts

References

15

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Jun S. Liu, Jesse D. Farmer, Willam S. Lane et al. · Cell · 1991 · 4.1K citations

, , +8

The Use of Diethyl Azodicarboxylate and Triphenylphosphine in Synthesis and Transformation of Natural Products

Oyo Mitsunobu · Synthesis · 1981 · 4.1K citations

, , +8

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

James P Griffith, Joseph L. Kim, Eunice E Kim et al. · Cell · 1995 · 838 citations · Full text

, , +14

Crystal structures of human calcineurin and the human FKBP12–FK506–calcineurin complex

Charles R. Kissinger, Hans E. Parge, Daniel R. Knighton et al. · Nature · 1995 · 762 citations

, , +12

Atomic Structure of FKBP-FK506, an Immunophilin-Immunosuppressant Complex

Gregory D. Van Duyne, Robert F. Standaert, P. Andrew Karplus et al. · Science · 1991 · 645 citations

, , +13