Concepedia

Potential antiedematous effects of intravitreous anti-VEGF, unrelated to VEGF neutralization

Francine Béhar‐Cohen, Marilyn Dernigoghossian, Charlotte Andrieu‐Soler, Rinath Levy, Raphael M. Cohen, Min Zhao

Drug Discovery Today · 2019 · 11 citations · 22 references

Open access

Concepts

MedicineSurgeryTargeted Drug DeliveryAngiogenesisEdemaGrowth Factor SignalingGrowth Factor TherapyVitreous Drug DeliveryAnti-vegf Ocular TherapyIntravitreal Anti-vascular Endothelial Growth Factor TherapyVascular Endothelial Growth FactorVascular Endothelial Growth Factor InhibitorsVascular Endothelial Growth Factor Receptor Signaling

References

22

Ranibizumab for Neovascular Age-Related Macular Degeneration

Philip J. Rosenfeld, David M. Brown, Jeffrey S. Heier et al. · New England Journal of Medicine · 2006 · 5.9K citations · Full text

Medicine, Ophthalmology, Surgery +12

Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration

New England Journal of Medicine · 2011 · 2.6K citations · Full text

Medicine, Ophthalmology, Pharmacotherapy +12

Comparisons of the Intraocular Tissue Distribution, Pharmacokinetics, and Safety of 125I-Labeled Full-Length and Fab Antibodies in Rhesus Monkeys Following Intravitreal Administration

Joyce Mordenti, R. Andrew Cuthbertson, Napoleone Ferrara et al. · Toxicologic Pathology · 1999 · 351 citations

Medicine, Ophthalmology, Pharmacokinetics +15

Ultrastructural Findings in the Primate Eye After Intravitreal Injection of Bevacizumab

Swaantje Peters, Peter Heiduschka, Sylvie Julien et al. · American Journal of Ophthalmology · 2007 · 231 citations

Medicine, Ophthalmology, Ocular Drug Delivery +15

Structure-Function Studies of Two Synthetic Anti-vascular Endothelial Growth Factor Fabs and Comparison with the Avastin™ Fab

Germaine Fuh, Ping Wu, Wei‐Ching Liang et al. · Journal of Biological Chemistry · 2005 · 186 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17