Concepedia

Improving breast cancer therapy using doxorubicin loaded solid lipid nanoparticles: Synthesis of a novel arginine-glycine-aspartic tripeptide conjugated, pH sensitive lipid and evaluation of the nanomedicine in vitro and in vivo

Gang Zheng, Meizhu Zheng, Ben Yang, Hui Fu, Yongqing Li

Biomedicine & Pharmacotherapy · 2019 · 119 citations · 64 references

DOIFull text

Open access

Concepts

Abstract

) of RGD-DOX-SLNs was 10.85 h and 39.12 ± 2.71 L/kg/h. in vitro and in vivo antitumor results indicate that RGD-DOX-SLNs might be a promising novel lipid carrier which could improve breast cancer therapy.

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