TREM2 Attenuates Aβ1-42-Mediated Neuroinflammation in BV-2 Cells by Downregulating TLR Signaling

Variant of <i>TREM2</i> Associated with the Risk of Alzheimer's Disease

Thorlákur Jónsson, Hreinn Stefánsson, Stacy Steinberg et al. · New England Journal of Medicine · 2012 · 2.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study

Victor L. Villemagne, Samantha C. Burnham, Pierrick Bourgeat et al. · The Lancet Neurology · 2013 · 2.3K citations

Medicine, Neurology, Neuroscience +17

TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model

Yaming Wang, Marina Cella, Kaitlin Mallinson et al. · Cell · 2015 · 1.8K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

Cameron R. Stewart, Lynda M. Stuart, Kim Wilkinson et al. · Nature Immunology · 2009 · 1.5K citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Microglia Initiate Central Nervous System Innate and Adaptive Immune Responses through Multiple TLRs

Julie K. Olson, Stephen D. Miller · The Journal of Immunology · 2004 · 1.2K citations · Full text

Life Sciences, Immunology, Neuroscience +17