Histopathology of Anterior Urethral Strictures: Toward a Better Understanding of Stricture Pathophysiology

Abstract

Chronic inflammation is prevalent in a significant percent of urethral stricture disease specimens. Associations with worse overall health suggest systemic mediators. Absent inflammation in bulbomembranous strictures suggests a unique pathophysiology in this region. The presence of inflammation did not affect surgical outcomes at mid-term followup.