Journal of the European Academy of Dermatology and Venereology · 2015 · 343 citations · 202 references
MedicineDermatologyDermatopathologyPediatric DermatologySkin Biopsy InterpretationInflammatory DermatosesInflammatory Skin DiseasesInflammatory Skin Disorders
Lichen sclerosus (LS) is an inflammatory skin disease that usually involves the anogenital area. All patients with symptoms or signs suspicious of lichen sclerosus should be seen at least once initially by a physician with a special interest in the disease in order to avoid delay in diagnosis, as early treatment may cure the disease in some and reduce or prevent scarring. The diagnosis is made clinically in most cases. Biopsies should only be performed under certain circumstances. The gold standard for treatment remains potent to very potent topical steroids; however, mild and moderate disease in boys and men may be cured by circumcision. Certain triggers should be avoided. http://www.euroderm.org/images/stories/guidelines/2014/S3-Guideline-on-Lichen-sclerosus.pdf http://www.awmf.org/fachgesellschaften/mitgliedsgesellschaften/visitenkarte/fg/deutsche-gesellschaft-fuer-gynaekologie-und-geburtshilfe-dggg.html.
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Long-term Management of Adult Vulvar Lichen Sclerosus
Andrew Lee, Jennifer Bradford, Gayle Fischer · JAMA Dermatology · 2015 · 381 citations · Full text
Medicine, Dermatology, Gynecology +17
Lichen sclerosus et atrophicus and autoimmunity—a study of 350 women
Ranjeny Thomas, C M Ridley, D. McGibbon et al. · British Journal of Dermatology · 1988 · 353 citations
Autoantibodies to extracellular matrix protein 1 in lichen sclerosus
Noritaka Oyama, Ien Chan, S. M. Neill et al. · The Lancet · 2003 · 313 citations
Does Treatment of Vulvar Lichen Sclerosus Influence Its Prognosis?
S.M. Cooper, XH Gao, Jenny Powell et al. · Archives of Dermatology · 2004 · 276 citations
Medicine, Dermatology, Pathology +13