Sensitivity of a continuous hot-melt extrusion and strand pelletization line to control actions and composition variation

Modernizing Pharmaceutical Manufacturing: from Batch to Continuous Production

Sau L. Lee, Thomas O’Connor, Xiaochuan Yang et al. · Journal of Pharmaceutical Innovation · 2015 · 832 citations · Full text

Pharmaceutical Formulation, Industrial Design, Pharmaceutical Supply Chain +5

Use of surfactants as plasticizers in preparing solid dispersions of poorly soluble API: Selection of polymer–surfactant combinations using solubility parameters and testing the processability

Alazar N. Ghebremeskel, Chandra Vemavarapu, Mayur Lodaya · International Journal of Pharmaceutics · 2006 · 316 citations

Materials Science, Chemical Engineering, Engineering +9

Development and evaluation of orally disintegrating tablets (ODTs) containing Ibuprofen granules prepared by hot melt extrusion

Andreas Gryczke, Silke Schminke, Mohammed Maniruzzaman et al. · Colloids and Surfaces B Biointerfaces · 2011 · 185 citations

Pharmaceutical Science, Pharmaceutical Technology, Ibuprofen Granules +3

Dissolution Similarity Requirements: How Similar or Dissimilar Are the Global Regulatory Expectations?

Dorys Argelia Diaz, Stephen T. Colgan, Connie Langer et al. · The AAPS Journal · 2015 · 176 citations · Full text

Economics, Mergers And Acquisitions, Finance +9

Using Residence Time Distributions (RTDs) to Address the Traceability of Raw Materials in Continuous Pharmaceutical Manufacturing

William E. Engisch, Fernando J. Muzzio · Journal of Pharmaceutical Innovation · 2015 · 168 citations · Full text