Updates to Binding MOAD (Mother of All Databases): Polypharmacology Tools and Their Utility in Drug Repurposing

The Protein Data Bank

Helen M. Berman · Nucleic Acids Research · 2000 · 39.8K citations

Life Sciences, Biochemistry, Bioinformatics +10

BLAST+: architecture and applications

Christiam Camacho, George Coulouris, Vahram Avagyan et al. · BMC Bioinformatics · 2009 · 23.2K citations · Full text

Life Sciences, Bioinformatics, Biology +13

DrugBank 5.0: a major update to the DrugBank database for 2018

David S. Wishart, Yannick Djoumbou-Feunang, An Chi Guo et al. · Nucleic Acids Research · 2017 · 8.8K citations · Full text

Medicine, Pharmacology, Drug Information +13

Extended-Connectivity Fingerprints

David Rogers, Mathew Hahn · Journal of Chemical Information and Modeling · 2010 · 7.6K citations

Pharmacy, Medicinal Chemistry, Drug Design +15

ChEMBL: a large-scale bioactivity database for drug discovery

Anna Gaulton, Louisa J. Bellis, A. Patrícia Bento et al. · Nucleic Acids Research · 2011 · 4.5K citations · Full text

Pharmacy, Bioinformatics, Chemical Biology +17