Neuroscience Letters · 2019 · 19 citations · 45 references
Life SciencesNeurobiologyNeuroscienceInflammationMolecular NeuroscienceNeuroimmunologyInflammatory SignalingInterferon ResponsesMicroglia BiologyNeurodegenerative DiseasesNeurodegenerative DisordersNeuroinflammationChronic NeuroinflammationInterferon Signaling ResponsesMicroglial Activation Gene ExpressionMicroglial Gene ExpressionNeuroinflammatory Cytokine ResponsesNeuroinflammatory CytokinesNeuroinflammatory MarkersNeuroinflammatory Signaling
cerebella, including MIG/CXCL9, MCP-1/CCL2, MIP-1α/CCL3, MIP-1β/CCL4, RANTES/CCL5, M-CSF, and IL-1α. Together, our results describe a novel activation pattern of interferon downstream signaling in pre-symptomatic NPC, as well as key inflammatory mediators that could serve as potential targets for NPC-specific anti-inflammatory therapy.
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Niemann-Pick C1 Disease Gene: Homology to Mediators of Cholesterol Homeostasis
Eugene D. Carstea, Jill A. Morris, Katherine Coleman et al. · Science · 1997 · 1.5K citations
Ebola virus entry requires the cholesterol transporter Niemann–Pick C1
Jan E. Carette, Matthijs Raaben, Anthony Wong et al. · Nature · 2011 · 1.3K citations · Full text