CPT Pharmacometrics & Systems Pharmacology · 2019 · 126 citations · 0 references
PharmacyBioinformaticsBiostatisticsClinical Data ManagementComputational PhenotypingEpidemiologic MethodsMixed Model AnalysisMixed-effects ModelsModel BuildingNonlinear Mixed-effects ModelingRandom Effects ModelingMixed Model SoftwareNonlinear Effects
In this tutorial, the various components of NONMEM will be described, and the basic steps of setting up NONMEM control stream files and data files will be demonstrated. Some basic concepts of nonlinear mixed effects modeling will be discussed, along with simple examples demonstrating how to use NONMEM to perform population analysis of clinical data.