Concepedia

The Notch signaling pathway inhibitor Dapt alleviates autism-like behavior, autophagy and dendritic spine density abnormalities in a valproic acid-induced animal model of autism

Ying‐Hua Zhang, Zhe Xiang, Yunjie Jia, HE Xue-ling, Lijun Wang, Weigang Cui

Progress in Neuro-Psychopharmacology and Biological Psychiatry · 2019 · 67 citations · 41 references

DOI

Concepts

References

41

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

Guomei Tang, Kathryn Gudsnuk, Sheng‐Han Kuo et al. · Neuron · 2014 · 1.2K citations · Full text

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Behavioral Alterations in Rats Prenatally Exposed to Valproic Acid: Animal Model of Autism

Tomasz Schneider, Ryszard Przewłocki · Neuropsychopharmacology · 2004 · 959 citations

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Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

Peter T. Tsai, Court Hull, YunXiang Chu et al. · Nature · 2012 · 911 citations · Full text

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Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

Jeffrey J. Hutsler, Hong Zhang · Brain Research · 2009 · 778 citations

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Expression of Notch-1 and Its Ligands, Delta-Like-1 and Jagged-1, Is Critical for Glioma Cell Survival and Proliferation

Benjamin Purow, Raqeeb Haque, Martha Noel et al. · Cancer Research · 2005 · 579 citations

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