Concepedia

Identification of a 3,3-difluorinated tetrahydropyridinol compound as a novel antitumor agent for hepatocellular carcinoma acting via cell cycle arrest through disturbing CDK7-mediated phosphorylation of Cdc2

Wu Bi, Ji‐Chang Xiao, Ruijie Liu, Liu-ying Zhou, Sai Zhang, Mei Yang, Pengfei Zhang

Investigational New Drugs · 2019 · 14 citations · 25 references

DOI

Concepts

References

25

Different Roles for Cyclins D1 and E in Regulation of the G<sub>1</sub>-to-S Transition

Dalia Resnitzky, Steven I. Reed · Molecular and Cellular Biology · 1995 · 468 citations · Full text

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Cytotoxic activity of Thai medicinal plants against human cholangiocarcinoma, laryngeal and hepatocarcinoma cells in vitro

Wiratchanee Mahavorasirikul, Vithoon Viyanant, Wanna Chai่jaroenkul et al. · BMC Complementary and Alternative Medicine · 2010 · 232 citations · Full text

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In vitro assembly of a functional human CDK7‐cyclin H complex requires MAT1, a novel 36 kDa RING finger protein.

Jean‐Pierre Tassan, Malika Jaquenoud, Andrew M. Fry et al. · The EMBO Journal · 1995 · 197 citations · Full text

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MicroRNA-93 activates c-Met/PI3K/Akt pathway activity in hepatocellular carcinoma by directly inhibiting PTEN and CDKN1A

Katsuya Ohta, Hiromitsu Hoshino, Jinhua Wang et al. · Oncotarget · 2014 · 171 citations · Full text

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Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells

Jun Yu, Qulian Guo, Qidong You et al. · Carcinogenesis · 2006 · 170 citations · Full text

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