The “bubble sign”: a novel way to detect a perforation after cold snare polypectomy

Abstract

To date, there have been no reported perforations with cold snare polypectomy (CSP). Therefore, possible signs of damage in the muscular layer remain unknown. We report the first cases of perforation using cold snare polypectomy, when two polyps < 20 mm in size were removed. Thus we are able to describe a new sign, the "bubble sign," for checking the integrity of the submucosal and muscular layer, that can help to detect potential injury in the colonic wall when cold snare polypectomy is performed.