Electrochemical Synthesis of 3‐Bromoimidazo[1,2‐a]pyridines Directly from 2‐Aminopyridines and <i>alpha</i>‐Bromoketones

Wen‐Qian Jian, Hai‐Bin Wang, Ke‐Si Du, Weiqiang Zhong, Jing‐Mei Huang

ChemElectroChem · 2019 · 21 citations · 44 references

Concepts

Abstract

Abstract A highly efficient co‐electrolysis of 3‐bromoimidazo[1,2‐a]pyridines has been developed in a simple undivided cell without any external oxidant. This protocol proceeds smoothly to provide the products with a broad substrate scope through a domino condensation/bromination sequence. Importantly, it can be easily scaled up.

References

44