Journal of Biomedical Nanotechnology · 2019 · 18 citations · 0 references
PharmacyPharmaceuticsPharmacologyDrug DeliveryNanoparticle Drug DeliveryTargeted Drug DeliveryDrug EncapsulationNanocarriers For TherapeuticsNanomaterials For Drug DeliveryNanomedicineNanoparticle Delivery SystemsNanoparticle FormulationsLymph Node TargetingNanoparticle-mediated Bioavailability EnhancementNanoparticlesPharmacokinetic EnhancementRenal Toxicity MitigationSerum Albumin UseTacrolimus Therapy
mice allo-heart transplantation verified the efficient lymphatic targeting of TAC-HSA-NPs, which is of crucial significance for immunosuppression in heart transplant recipients. Overall, our study proposed a new nanoformulation of TAC-HSA-NPs and confirmed the potential application in organ transplantation.