Concepedia

Proximal Tubule Autophagy Differs in Type 1 and 2 Diabetes

Shinsuke Sakai, Takeshi Yamamoto, Yoshitsugu Takabatake, Atsushi Takahashi, Tomoko Namba‐Hamano, Satoshi Minami, Ryuta Fujimura, Hiroaki Yonishi, Jun Matsuda, Atsushi Hesaka,

Journal of the American Society of Nephrology · 2019 · 89 citations · 40 references

DOIFull text

Open access

Abstract

Autophagic activity in PTECs is mainly regulated by insulin. Consequently, autophagic activity differs in types 1 and 2 diabetic nephropathy, which should be considered when developing strategies to treat diabetic nephropathy by modulating autophagy.

References

40

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