Concepedia

TPP1 OB-fold domain protein suppresses cell proliferation and induces cell apoptosis by inhibiting telomerase recruitment to telomeres in human lung cancer cells

Jinfang Zhu, Weiran Liu, Chen Chen, Hua Zhang, Dongsheng Yue, Chenguang Li, Lianmin Zhang, Liuwei Gao, Yansong Huo, Chang Liu,

Journal of Cancer Research and Clinical Oncology · 2019 · 12 citations · 23 references

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Concepts

References

23

Telomere states and cell fates

Elizabeth H. Blackburn · Nature · 2000 · 1.4K citations

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The POT1–TPP1 telomere complex is a telomerase processivity factor

Feng Wang, Elaine R. Podell, Arthur J. Zaug et al. · Nature · 2007 · 709 citations · Full text

, , +10

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

X. Zhang, V L Mar, Wen Zhou et al. · Genes & Development · 1999 · 699 citations · Full text

, , +16

TPP1 is a homologue of ciliate TEBP-β and interacts with POT1 to recruit telomerase

Huawei Xin, Dan Liu, Ma Wan et al. · Nature · 2007 · 475 citations

, , +5

Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands

Jean‐François Riou, Lionel Guittat, Patrick Mailliet et al. · Proceedings of the National Academy of Sciences · 2002 · 392 citations

, , +17