Concepedia

Lipopolysaccharide and interferon-γ team up to activate HIF-1α via STAT1 in normoxia and exhibit sex differences in human aortic valve interstitial cells

Iván Parra‐Izquierdo, Irene Castaños‐Mollor, Javier López, Cristina Gómez, J. Alberto San Román, Mariano Sánchez Crespo, Carmen García‐Rodríguez

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2019 · 71 citations · 36 references

DOI

Concepts

References

36

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

Jordi Rius, Mónica Gumá, Christian Schachtrup et al. · Nature · 2008 · 1.6K citations · Full text

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Characterization of the early lesion of 'degenerative' valvular aortic stenosis. Histological and immunohistochemical studies.

Catherine M Otto, Johanna Kuusisto, Dennis D. Reichenbach et al. · Circulation · 1994 · 1.3K citations

, , +14

Bone Formation and Inflammation in Cardiac Valves

Emile R. Mohler, Francis H. Gannon, Carol Reynolds et al. · Circulation · 2001 · 1K citations

, , +17

Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasis

Norihiko Takeda, Ellen L O'Dea, Andrew L. Doedens et al. · Genes & Development · 2010 · 616 citations · Full text

, , +17

Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genes

HyeonJoo Cheon, George R. Stark · Proceedings of the National Academy of Sciences · 2009 · 312 citations

, , +17