Amelioration of muscle wasting by glucagon‐like peptide‐1 receptor agonist in muscle atrophy

Abstract

GLP-1R agonists ameliorate muscle wasting by suppressing MSTN and muscle atrophic factors and enhancing myogenic factors through GLP-1R-mediated signalling pathways. These novel findings suggest that activating GLP-1R signalling may be useful for the treatment of atrophy-related muscular diseases.