Concepedia

Molecular grouping and outcomes of young children with newly diagnosed ependymoma treated on the multi-institutional SJYC07 trial

Santhosh A. Upadhyaya, Giles Robinson, Arzu Onar‐Thomas, Brent A. Orr, Catherine A. Billups, Daniel C. Bowers, Anne Bendel, Tim Hassall, John R. Crawford, Sonia Partap,

Neuro-Oncology · 2019 · 83 citations · 38 references

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Abstract

In this prospectively treated cohort of young children with ependymoma, ST-EPN-RELA tumors had a more favorable outcome than reported from retrospective data. Histologic grade did not impact outcome. PF-EPN-A with 1q gain and subtotal resection were associated with inferior outcomes.

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Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

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