Concepedia

Inhibition of MRP4 alleviates sepsis-induced acute lung injury in rats

Wenfang Xia, Huanming Zhang, Pan Zhou, Guang Li, Qingshan Zhou, Dan Hu, Yu Liu

International Immunopharmacology · 2019 · 29 citations · 24 references

DOI

Concepts

References

24

Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: A trend analysis from 1993 to 2003*

Viktor Y. Dombrovskiy, Andrew Martin, Jag Sunderram et al. · Critical Care Medicine · 2007 · 1.3K citations

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The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

Inka Leier, Gabriele Jedlitschky, Ulrike Buchholz et al. · Journal of Biological Chemistry · 1994 · 856 citations · Full text

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ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation

Olga Tornavaca, Minghao Chia, Neil Dufton et al. · The Journal of Cell Biology · 2015 · 575 citations · Full text

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The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs

Glen Reid, Peter R. Wielinga, Noam Zelcer et al. · Proceedings of the National Academy of Sciences · 2003 · 539 citations · Full text

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Sepsis and Endothelial Permeability

Warren L. Lee, Arthur S. Slutsky · New England Journal of Medicine · 2010 · 523 citations

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