Dietary Palmitoleic Acid Attenuates Atherosclerosis Progression and Hyperlipidemia in Low‐Density Lipoprotein Receptor‐Deficient Mice

Abstract

Dietary-supplemented palmitoleate reduces atherosclerosis development in LDLR-KO mice, and is associated with improvement of lipid and glucose metabolism and favorable changes in regulatory genes involved in lipogenesis and inflammation. These findings imply the potential role of dietary palmitoleate in the prevention of cardiovascular disease and diet-induced metabolic disorders.