Anticancer Research · 2019 · 13 citations · 10 references
MedicineClinical SciencesSurgeryBacteriologyGastroenterologySurgical PathologyFistula ManagementPancreatic DiseasesPancreatic PathologyPancreatic SurgeryPreoperative EvaluationPreoperative Risk AssessmentClinicopathological CorrelationPostoperative Fistula ComplicationsPostoperative Fistula DetectionPostoperative Fistula FormationPostoperative Pancreatic ComplicationsPostoperative Pancreatic Fistula DetectionUnivariate AnalysisUnivariate Risk Analysis
BACKGROUND: The aim of the present study was to investigate risk factors for the development of grade C compared to grade B cases of postoperative pancreatic fistula (POPF). MATERIALS AND METHODS: Clinicopathological data from 43 patients who developed grade B or C POPF were retrospectively analyzed. The following types of factors were analyzed: Patient-related, surgery-related, and pancreas-related, including the value of the drain amylase and the detection of gram-negative rod bacteria within the first 7 postoperative days (PODs). RESULTS: Univariate analysis showed that male sex (p=0.0492) and detection of gram-negative rods within the first 7 PODs (p=0.0010) were risk factors for development of grade C POPF. Only detection of gram-negative rods within the first 7 PODs was a significant factor after multivariate analysis (p=0.0027). CONCLUSION: Sensitive and specific predictive criteria for early detection of grade C POPF should be developed to allow for a management approach appropriately tailored to this condition.
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Assessment of Complications After Pancreatic Surgery
Michelle L. DeOliveira, Jordan M. Winter, Markus Schäfer et al. · Annals of Surgery · 2006 · 796 citations · Full text
Medicine, Clinical Sciences, Surgery +17