Resistin up-regulates LPL expression through the PPARγ-dependent PI3K/AKT signaling pathway impacting lipid accumulation in RAW264.7 macrophages

The hormone resistin links obesity to diabetes

Claire M. Steppan, Shannon T. Bailey, Savitha Bhat et al. · Nature · 2001 · 4.8K citations

Life Sciences, Biochemistry, Endocrinology +12

PPARalpha and PPARgamma activators direct a distinct tissue‐specific transcriptional response via a PPRE in the lipoprotein lipase gene.

Kristina Schoonjans, Julia Peinado‐Onsurbe, Anne‐Marie Lefebvre et al. · The EMBO Journal · 1996 · 1.2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation

Ajay Chawla, Yaacov Barak, László Nagy et al. · Nature Medicine · 2001 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +17

Resistin is expressed in human macrophages and directly regulated by PPARγ activators

Lisa Patel, Amy C Buckels, Ian J. Kinghorn et al. · Biochemical and Biophysical Research Communications · 2003 · 916 citations

Life Sciences, Cell Biology, Immunology +14

Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein.

Ulrike Beisiegel†, Wolfgang Weber, Gunilla Bengtsson-Olivecrona · Proceedings of the National Academy of Sciences · 1991 · 626 citations

Life Sciences, Biochemistry, Cell Biology +13