Fungal extracts stimulate solitary chemosensory cell expansion in noninvasive fungal rhinosinusitis

Abstract

Although fungal antigens are known to potentiate immune response through innate cytokines, including IL-25, the early expansion of SCCs in the presence of fungus has not been described. This early event in the pathogenesis of noninvasive fungal rhinosinusitis may represent a target for intervention.