Cu(OTf)<sub>2</sub>-Promoted 1,4-Addition of Alkyl Bromides to Dehydroalanine

Jung‐Ah Shin, Jiheon Kim, Hongsoo Lee, Hongsoo Lee, Sura Ha, Hee‐Yoon Lee, Hee‐Yoon Lee

The Journal of Organic Chemistry · 2019 · 20 citations · 34 references

Concepts

Abstract

-mediated addition of alkyl bromides to dehydroalanine (Dha) derivatives including dipeptides and tripeptides in good to high yields under an aqueous medium was developed. This protocol allows selective and biocompatible access to various amino acid units from Dha derivatives.

References

34