Concepedia

A NIK–SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB

Zixu Liu, Katrina B. Mar, Natasha W. Hanners, Sofya S. Perelman, Mohammed Kanchwala, Chao Xing, John W. Schoggins, Neal M. Alto

Nature · 2019 · 75 citations · 42 references

Concepts

Life SciencesImmunologyMolecular BiologyCell SignalingInflammationSignal TransductionInflammatory Cell ResponsesInflammatory Cell SignalingInflammatory SignalingInnate Immune ActivationInnate Immune Signaling PathwaysNod-like ReceptorsInnate Immune Signaling ModulationNuclear Factor Kappa B ActivationNuclear Factor Kappa B InhibitionNuclear Factor Kappa B ModulationNuclear Factor Kappa B SignalingPro-inflammatory Signaling PathwaysTargeted Gene Silencing

References

42

<tt>edgeR</tt> : a Bioconductor package for differential expression analysis of digital gene expression data

Mark D. Robinson, Davis J. McCarthy, Gordon K. Smyth · Bioinformatics · 2009 · 44.5K citations · Full text

Life Sciences, Bioinformatics, Biostatistics +14

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

Yang Liao, Gordon K. Smyth, Wei Shi · Bioinformatics · 2013 · 29.1K citations · Full text

Life Sciences, Bioinformatics, Biology +14

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

Daehwan Kim, Geo Pertea, Cole Trapnell et al. · Genome biology · 2013 · 13.7K citations · Full text

Life Sciences, Bioinformatics, Genetics +14

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

Cole Trapnell, Adam Roberts, Loyal A. Goff et al. · Nature Protocols · 2012 · 12.9K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +12

A diverse range of gene products are effectors of the type I interferon antiviral response

John W. Schoggins, Sam J. Wilson, Maryline Panis et al. · Nature · 2011 · 2.5K citations

Life Sciences, Immunology, Molecular Biology +16