Aging · 2019 · 193 citations · 28 references
MedicineGeneticsOncologyCancer GeneticsGene ExpressionMolecular OncologyCancer BiomarkersKidney CancerMolecular Tumor ProfilingNoncoding Rna In CancerRenal Cell CarcinomaRenal NeoplasmsCopy Number GainsCox RegressionGene Expression SignaturesMtor Pathway DysregulationOncogene Copy Number GainPrognostic Gene SignaturesRegulatorsRenal Cell Carcinoma Biomarkers
was related to activations of adipogenesis and mTOR pathways. Thus, we for the first time determined genetic alterations of m6A regulators in ccRCC and found a significant relationship between the alterations and worse clinical characteristics. The findings provide us clues to understand epigenetic modification of RNA in ccRCC.
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Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2018 · 17K citations · Full text
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
Jianjiong Gao, Bülent Arman Aksoy, Uğur Doğrusöz et al. · Science Signaling · 2013 · 15.9K citations · Full text
Medicine, Bioinformatics, Oncology +17
Molecular signatures database (MSigDB) 3.0
Arthur Liberzon, Aravind Subramanian, Reid M. Pinchback et al. · Bioinformatics · 2011 · 7.7K citations · Full text
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
Dan Dominissini, Sharon Moshitch-Moshkovitz, Schraga Schwartz et al. · Nature · 2012 · 5K citations