Gene signatures and prognostic values of m6A regulators in clear cell renal cell carcinoma – a retrospective study using TCGA database

Jingcheng Zhou, Jiangyi Wang, Baoan Hong, Kaifang Ma, Haibiao Xie, Lei Li, Kenan Zhang, Bowen Zhou, Lin Cai, Kan Gong

Aging · 2019 · 193 citations · 28 references

DOIFull text

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Concepts

Abstract

was related to activations of adipogenesis and mTOR pathways. Thus, we for the first time determined genetic alterations of m6A regulators in ccRCC and found a significant relationship between the alterations and worse clinical characteristics. The findings provide us clues to understand epigenetic modification of RNA in ccRCC.

References

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