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Examining P-gp efflux kinetics guided by the BDDCS – Rational selection of in vitro assay designs and mathematical models

Molecular PharmacologyPharmacokinetic ModelingBiochemistryPhysiologically-based Pharmacokinetic ModelingMedicineP-gp Efflux KineticsPharmacodynamic ModelingPharmacologyVitro Assay DesignsPharmacokineticsMathematical ModelsDrug DiscoveryPharmaceutical Research