Topology effects on protein–polymer block copolymer self-assembly

Abstract

Bioconjugates made of the model red fluorescent protein mCherry and synthetic polymer blocks show that topology, <italic>i.e.</italic> the BA, BA₂, ABA and ABC chain structure of the block copolymers, where B represents the protein and A and C represent polymers, has a significant effect on ordering transitions and the type and size of nanostructures formed during microphase separation.