Concepedia

MiRNA-21 functions in ionizing radiation-induced epithelium-to-mesenchymal transition (EMT) by downregulating PTEN

Zheng Liu, Xin Liang, Xueping Li, Xiaodan Liu, Maoxiang Zhu, Yongqing Gu, Ping‐Kun Zhou

Toxicology Research · 2019 · 51 citations · 42 references

DOIFull text

Open access

Concepts

Abstract

the PTEN/Akt pathway. Targeting miR-21 is implicated as a novel therapeutic strategy for the prevention of RIPF.

References

42

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

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Circulating microRNAs as stable blood-based markers for cancer detection

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Prediction of Mammalian MicroRNA Targets

Benjamin P. Lewis, I‐hung Shih, Matthew W. Jones-Rhoades et al. · Cell · 2003 · 5.2K citations · Full text

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MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

Thomas Thum, Carina Gross, Jan Fiedler et al. · Nature · 2008 · 2.3K citations

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Evidence that fibroblasts derive from epithelium during tissue fibrosis

Masayuki Iwano, David Plieth, Theodore M. Danoff et al. · Journal of Clinical Investigation · 2002 · 1.8K citations · Full text

, , +17