Expression of a soluble IL-10 receptor enhances the therapeutic effects of a papillomavirus-associated antitumor vaccine in a murine model

Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen.

K Y Lin, Frank Guarnieri, Kevin F. Staveley-O’Carroll et al. · PubMed · 1996 · 1K citations

Medicine, Immunology, Oncology +17

Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial

Cornelia L. Trimble, Matthew P. Morrow, Kimberly A. Kraynyak et al. · The Lancet · 2015 · 714 citations

Medicine, Immunology, Oncology +17

Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8+ T cell responses

Melissa Precopio, Michael R. Betts, Janie Parrino et al. · The Journal of Experimental Medicine · 2007 · 486 citations · Full text

Life Sciences, Immunology, Infectious Diseases +16

Clearance of persistent HPV infection and cervical lesion by therapeutic DNA vaccine in CIN3 patients

Tae Jin Kim, Hyun‐Tak Jin, Soo Young Hur et al. · Nature Communications · 2014 · 258 citations · Full text

Medicine, Immunology, Oncology +17

Vaccination in Humans Generates Broad T Cell Cytokine Responses

Stephen C. De Rosa, Fabien X. Lü, Joanne Yu et al. · The Journal of Immunology · 2004 · 202 citations

Life Sciences, Cell Biology, Immunology +17