Concepedia

Investigation of B,C-ring truncated deguelin derivatives as heat shock protein 90 (HSP90) inhibitors for use as anti-breast cancer agents

Ho Shin Kim, Van-Hai Hoang, Mannkyu Hong, Kyung Chul Kim, Jihyae Ann, Cong-Truong Nguyen, Ji Hae Seo, Hoon Choi, Jun Yong Kim, Kyu-Won Kim,

Bioorganic & Medicinal Chemistry · 2019 · 25 citations · 17 references

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17

Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?

Clinical Cancer Research · 2012 · 903 citations · Full text

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Altered Hsp90 function in cancer: A unique therapeutic opportunity

Rochelle Bagatell, Luke Whitesell · Molecular Cancer Therapeutics · 2004 · 304 citations · Full text

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Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer

Qing Cheng, Jeffrey T. Chang, Joseph Geradts et al. · Breast Cancer Research · 2012 · 184 citations · Full text

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Inhibition of Hsp90 Down-regulates Mutant Epidermal Growth Factor Receptor (EGFR) Expression and Sensitizes EGFR Mutant Tumors to Paclitaxel

Ayana Sawai, Sarat Chandarlapaty, Heidi Greulich et al. · Cancer Research · 2008 · 178 citations · Full text

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Structural Basis for Depletion of Heat Shock Protein 90 Client Proteins by Deguelin

Seung Hyun Oh, Jong Kyu Woo, Yasemin D. Yazici et al. · JNCI Journal of the National Cancer Institute · 2007 · 146 citations · Full text

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