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Impact of NUDT15 genetics on severe thiopurine-related hematotoxicity in patients with European ancestry

DOIFull Paper Access

96

Citations

13

References

2019

Year

Elke Schaeffeler, Simon U. Jaeger, Verena Klumpp, Jun J. Yang, Svitlana Igel, Laura Hinze, Martin Stanulla, Matthias Schwab
Genetics in Medicine

Abstract

Taken together, NUDT15 and TPMT genetics explain ~50% of severe thiopurine-related hematotoxicity, providing a compelling rationale for additional preemptive testing of NUDT15 genetics not only in Asians, but also in Europeans.

References

YearCitations

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