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Synthesis of novel 8-(het)aryl-6H-pyrano[4′,3′:4,5]thieno[3,2-b]pyridines by 6-endo-dig cyclization of Sonogashira products and halolactonizations with Cu salts/NXS. Preliminary antitumor evaluation

Medicinal Chemistry6-Endo-dig CyclizationNatural SciencesCu Salts/nxsOrganic ChemistryChemistryPharmacologyPreliminary Antitumor EvaluationSynthetic ChemistryNatural Product Synthesis