Design, synthesis and biological evaluation of coumarin-3-carboxamides as selective carbonic anhydrase IX and XII inhibitors

Extra Precision Glide:  Docking and Scoring Incorporating a Model of Hydrophobic Enclosure for Protein−Ligand Complexes

Richard A. Friesner, Robert B. Murphy, Matthew P. Repasky et al. · Journal of Medicinal Chemistry · 2006 · 6.7K citations

Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments

G. Madhavi Sastry, Matvey Adzhigirey, Tyler Day et al. · Journal of Computer-Aided Molecular Design · 2013 · 5.8K citations

Virtual Screening, Hit Identification, Drug Target +13

The Carbon Dioxide Hydration Activity of Carbonic Anhydrase

Raja G. Khalifah · Journal of Biological Chemistry · 1971 · 1.9K citations · Full text

Bovine Carbonic Anhydrase, Carbon Sequestration, Carbonization +14

Substantial contribution of extrinsic risk factors to cancer development

Song Wu, Scott Powers, Wei Zhu et al. · Nature · 2015 · 645 citations · Full text

Cancer Risk, Medicine, Epidemiology Of Cancer +9

Non-Zinc Mediated Inhibition of Carbonic Anhydrases: Coumarins Are a New Class of Suicide Inhibitors

Alfonso Maresca, Claudia Temperini, Hoan Vu et al. · Journal of the American Chemical Society · 2009 · 504 citations · Full text

Pharmacotherapy, Chemical Biology, Enzyme Active Site +17